IMAGE MICROARRAYS DERIVED FROM TISSUE MICROARRAYS (IMA-TMA): NEW RESOURCE FOR COMPUTER-AIDED DIAGNOSTIC ALGORITHM DEVELOPMENT

Background: Conventional tissue microarrays (TMAs) consist of cores of tissue inserted into a recipient paraffin block such that a tissue section on a single glass slide can contain numerous patient samples in a spatially structured pattern.Scanning TMAs into digital slides for subsequent analysis by computer-aided diagnostic (CAD) algorithms ANTI-

The title compound, C12H11N3O2, a hemiamidal, was synthesized by solvent-free aldol condensation at room temperature by grinding picolinamide with isonicotinaldehyde in a 1:1 molar ratio.In the molecule, the two pyridine rings are inclined to one another by 58.75 (6)°.They are linked, at positions 2 and 4, by the hemiamidal bridg